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CNV Analysis

Comparative genomic hybridization(CGH)는 genome 상에 존재하는 CNV(copy-number variations) 연구에 사용됩니다

Example for workflow & requirement

Affymetrix CytoScanHD array

  • Benefit

    70만개의 SNPs 마커와 260만개 이상의 copy number 마커를 가진 CtyoScanHD를 출시하여 가장 작은 크기의 structural changes를 분석 할 수 있습니다. 또한 UPD(uniparental disomy)와 IBD(identical-by-cescent)과 연관된 LOH(loss of heterozygosity)를 발굴 할 수 있습니다.

  • Workflow

  • Sample requirement

    DNA Amount: 250ng
    DNA Qualification: 260/280 1.8~2.0, 260/230 ratio of over 1.5, (by gel image) no RNA, no degradation

  • Turnaround time

    DNA QC: 2~3 days
    5 days for 48 arrays

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